设计了一种靶向载体,包含FRT序列后面跟着lacZ基因,一个loxP位点,一个诺卡因抗性基因元件,再次是FRT序列和一个loxP位点(FRT-lacZ-loxP-Neo-FRT-loxP),这些位于microRNA的茎环结构上游,紧接着是microRNA茎环结构下游的一个loxP位点。 (来源:J:181752)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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