设计了一种构建,通过将C端的糖磷脂酰肌醇(GPI)锚信号替换成myc标签,并将其克隆到cos.Tet载体中。cos.Tet载体是一种基于cosmid的表达载体,来源于叙利亚仓鼠Prnp基因。构建出了Line 8015(来源:J:180145)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB.129S7(B6)-Prnptm1Cwe/J
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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