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在exon 31的5995位点，C到T的突变导致Arg2110变为Trp，这是通过同源重组在31号外显子和32号内含子之间插入了一个floxed neo cassette。随后，通过Cre介导的重组移除了neo cassette。P1a蛋白在杂合子和纯合子小鼠的初级角质细胞提取物中的表达降低。(来源：J:179812)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
