Dnah5^b2b1134Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to G substitution at coding nucleotide 7971 in exon 48 of the cDNA (c.7971T>G, NM_133365). This changes the asparagine residue to lysine at position 2657 of the encoded protein (p.N2657K). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Dnah5b2b1134Clo, and may be present in stocks carrying this mutation.