第六和第七外显子被替换成新霉素抗性基因 cassette。RT-PCR 和 Western blot 的结果显示,两种异构体的基因表达均受到了干扰。(来源:J:180524)
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Exons 6 and 7 were replaced with a neomycin selection cassette. RT-PCR and Western blot analysis confirmed that gene expression of both isoforms was disrupted. (J:180524)