Ctnnb1^tm3Kba

A point mutation was introduced into exon 4 resulting in a D164A mutation and a floxed hygromycin cassette was inserted via homologous recombination. In a second recombination event, a premature stop codon followed by a frameshift mutation were introduced at amino acid position 673 in exon 13 and this exon was fused to exon 15. (J:178971)