一个新合成的cassette替换了2号外显子到5号外显子之间的序列。 Western blot分析证实脾细胞中没有蛋白表达。(来源:J:180356)
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A neo cassette replaced the sequence between the translation initiation site in exon 2 through part of exon 5. Western blot analysis confirmed the absence of protein expression in splenic cells. (J:180356)