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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(ED-L2-IL1RN/IL1B)#Tcw
Alias:
L2-IL-1Beta
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基础信息
表型特征
文献报道
Epstein-Barr病毒的ED-L2启动子驱动表达一种修改的人类IL1B基因。这种修改的人类IL1B基因包含了IL1RN信号序列,以及编码17千道尔顿成熟人IL1B的cDNA。我们构建了两条生产线,一条高表达,一条低表达。(来源:J:180282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5308012
C57BL/6 x SJL
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插入
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2
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8
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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