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中文
通过Cre介导的重组，Is(2)46Ddu和Tg(Hoxd9/lacZ/neo)3Ddu之间的操作诱导了一个240kb的缺失。这个区域包含了调控全局的区域(GCR)和Prox增强子区域，它们影响到Hoxd基因在趾端的表达。在E12.5时，发育中的趾发育中Hoxd13的mRNA表达减少了60%的野生型水平。Evx2、Hoxd12和Hoxd11的表达也受到了影响。(来源：178930)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
