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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gt(ROSA)26Sor
tm1(CAG-Bmpr1a)Que
Alias:
Rosa26
CAG-loxpstoploxp-caBmpr1a
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基础信息
表型特征
文献报道
在CAG启动子上游,放置了一个可以被敲除的诺卡因(NEO)序列,随后是一个4X polyA插件,后面跟着Bmpr1a和polyA构建。这个序列中有一个甘氨酸-苏氨酸区域内的单个谷氨酰胺替换为天冬氨酸。(来源:J:166768)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5305709
Not Specified
Targeted
插入
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6
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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