在CD8基因调控区的cII和cIII两个DNase I敏感位点之间,插入了一个带有5' loxP位点和被敲除的人类CD2调控区的诺卡因抗性基因座。随后,通过Cre介导的重组,去除了neo cassette。(来源:J:179326)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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