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中文
插入L1L2_Bact_P cassette导致了11号染色体(基因组构建GRCm39)上一个3495碱基对的缺失，起始于590,490,32位，终于59,052,527位。这个缺失导致了功能关键区段的丧失。该 cassette 包含FRT位点、lacZ序列和一个loxP位点，其中第一个loxP位点后面跟着一个由人类β-actin启动子驱动的诺卡因抗性基因，接着是SV40polyA，然后是第二个FRT位点和第二个loxP位点。欲了解针对此类IKMC等位基因的靶向策略详情，请参阅http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml(参考文献J:157064)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
