Tln1^tm1.1Bpet

Exon 10 was replaced with one in which a point mutation results in the amino acid substitution of leucine with arginine at position 325 (p.L325R) in the encoded protein. A loxP site flanked neomycin resistance gene cassette that was inserted into intron 10 was removed by subsequent cre-mediated recombination. (J:177971)