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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(RNU6-RNAi:Mpp5)13Wij
Alias:
shPals1
flox
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基础信息
表型特征
文献报道
这个转基因包含了人类的RNU6启动子,驱动对Mpp5的短发RNA的表达,短发RNA前面有一个可删除的puro载体,后面跟着木鼠肝炎病毒的后转录调控元件(WPRE序列)。ES细胞系7和13成功产生了生殖系传播。(来源:J:178056)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5297927
129P2/OlaHsd
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2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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