这个转基因包含了人类的RNU6启动子,驱动对Mpp5的短发RNA的表达,短发RNA前面有一个可删除的puro载体,后面跟着木鼠肝炎病毒的后转录调控元件(WPRE序列)。ES细胞系7和13成功产生了生殖系传播。(来源:J:178056)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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