在第3外显子上游插入了loxP位点,下游则插入了带有fluorotagged hygro标记的载体。通过Cre介导的重组,去除了hygro cassette和第3外显子。前脑提取物的 Western blot 分析证实了蛋白表达的缺失。(来源:J:177836)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count