在第1外显子插入了lacZ基因和一个floxed neo cassette,随后通过Cre介导的重组移除了neo cassette。通过 hippocampus组织的定量RT-PCR,确认了转录表达的缺失。(来源:J:177671, J:178055)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count