使用了重组酶驱动的 cassette exchange 方法,将针对 Brachyury (T) 基因的两个短发卡宾 RNAi 特定插入到 tetO 后跟 PGK 拓扑异构酶驱动的 Gt(ROSA)26Sortm2Bgh 基因座中。RNAi 的表达需要通过添加多西环素(/doxycycline)来驱动。(来源:J:173434)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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