"链球菌毒素A基因和一个含floxed neo cassette的片段替换了HS5-1(一个神经特异性转录增强子)。通过Cre介导的重组,删除了floxed选择 cassette。P9神经组织的RT-PCR结果显示,簇前5'端基因的转录表达适度减少,3'端基因表达显著减少,除了Pcdhac2。RT-PCR确认了簇在胶质细胞和肾脏中转录表达的增加。(文献引用:J:118324, J:177466)"
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count