在反转录方向,通过FRT座点插入了一段耐氨苄青霉素抗性基因 cassette,同时在内含子53的位置加入了一个loxP座。接着在exon54位置放置了第二个loxP座。通过Cre介导的重组,删除了含FRT座点的片段,使得耐氨苄青霉素的抗性基因 cassette保持不变。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入,基因内删除
--
1
8
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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