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中文
将Cre重组酶的编码序列和一个由loxP标记的诺卡因选择座（neomycin cassette）插入Eomes基因的起始外显子1位点，导致5'编码区域大约500bp的缺失。实验在CCE ES细胞中进行，成功靶向的ES细胞短暂转染了携带Cre的质粒，以去除诺卡因座。随后，这些细胞被用于产生生殖细胞嵌合体。Cre mRNA的表达再现了内源性Eomes的表达模式。（来源：J:176969）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
