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中文
在经同源重组，FRT flanked Neo/Kan筛选 cassette 和 loxP 立即插入了第4外显子上游，而后一个 loxP 立即插入了第6外显子下游。通过Cre介导的重组，4-6号外显子被删除。睾丸和MEFs（小鼠胚胎成纤维细胞）的RT-PCR和 Western Blot分析证实了纯合子小鼠中野生型RNA和蛋白质表达的缺失。然而，RT-PCR检测到来自纯合子小鼠睾丸的，包含7和9号外显子的微小转录本表达。(来源：J:215857)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
