在exon 4的上游插入了一个loxP位点。接着在exon 6之后插入了一个由FRT引导的neo cassette,带有3'的loxP位点。通过Flp介导的重组,neo cassette被移除,导致exons 4到6都被留下了loxP标记的内切位点。(来源:J:177405)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count