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中文
生成了一个靶向载体，用于将带有Frt内切酶切点的PGK-neo-cre cassette插入G4 ES细胞的Noto基因座，替换exon 2。通过筛选出的正确靶向细胞，产生了作为始祖异种嵌合体的后代，这些后代与CD1(ICR)动物进行了交配以进行遗传传递。随后，这些后代与Tg(ACTGLPe)9205Dym品系杂交，以剔除PGK-neo序列。(来源：J:177256)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
