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中文
通过同源重组，一个靶向载体被构建，用于将dsRed-IRES-cre/ERT2-pA-Frt-neo-Frt元件插入Lgr5基因座的第1外显子起始密码子后(删除第1外显子剩余部分和内含子1的切割点，共212bp)，在C2 ES细胞中。正确靶向的克隆通过转染Flpe质粒来消除neo cassette。(来源：J:177145)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
