通过Cre介导的重组,去除了exon 1和neo cassette,蛋白表达缺失通过脑和脾组织的 Western blot 分析得到了确认(来源:J:176560)
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Cre-mediated recombination removed exon 1 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on brain and spleen extracts. (J:176560)