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中文
构建了一个带有条件性Rnu6(U6)启动子（通过loxP引导的neo cassette的插入破坏）的敲降载体，该启动子驱动针对小鼠Bccip的特异性short hairpin RNA。载体被注入FVB/N的受精卵中。产生了两条奠基品系，4号和13号。对4号品系进行了更深入的研究。Cre重组会剪切掉含loxP的neo cassette，恢复Rnu6启动子的功能，从而驱动Bccip基因的反义shRNA转录，实现Bccip基因的RNA干扰。(来源：J:176115)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
