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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(KRT14-Kitl*)4XTG2Bjl
Alias:
TG2
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基础信息
表型特征
文献报道
转基因构建包含了一段由人角蛋白14(KRT14)启动子控制的突变小鼠Kitl(Kit配体)基因cDNA,其中去除了第164到165位氨基酸之间的主要高效剪切位点(源于文献J:113444)。随后建立了4XTG2转基因品系。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5288393
(C57BL/6 x SJL)F1
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1
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9
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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