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中文
CMV启动子驱动对人类KRAS小分子基因的泛表达，该基因发生了一个核苷酸替换，导致第12位的缬氨酸替换为甘氨酸，并带有内源性启动子（IRES），以及EGFP标记。小分子基因前有floxed neo cassette。需要Cre介导的重组来激活发生在约40-50%人类结直肠腺瘤和癌变中的Kras突变。(来源：J:122904)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
