在内皮1中发生了一次逆转录病毒插入的基因陷阱载体。RT-PCR和 Western blot 分析证实了纯合小鼠心、脑、肺、肝、肾和胰腺中没有mRNA和蛋白质的表达。(来源:J:250411)
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A retroviral insertion of a gene trap vector occurred in intron 1. RT-PCR and western blot analysis confirmed the absence of mRNA and protein expression in heart, brain, lung, liver, kidney and pancreas from homozygous mice. (J:250411)