在内源性终止密码子后方插入了8个碱基的IRES-cre/ERT2和FRT引导的诺卡因筛选元件。随后,通过与Gt(ROSA)26Sortm1(FLP1)Dym小鼠品系杂交,将筛选元件去除了。内源基因功能保持不变。(来源:J:174914)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
2
77

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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