Tg(NEFL*E397K)#Milg

This transgene constitutively expresses human neurofilament light (about 9.7 kb genomic fragment including the 1.7 kb endogenous 5' promoter sequence) with a G-to-A nucleotide substitution at nucleotide 3332 resulting in a glutamic acid to lysine mutation at position 397. Four lines were made, 661, 727, 728, and 730. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:173771)