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在exon 1的编码区域，包括起始翻译位点，通过同源重组被一个带有floxed pgk-neo cassette的序列替换。RT-PCR、免疫印迹和免疫组化分析证实了纯合小鼠肝脏中没有表达(来源：J:174134)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
