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中文
转基因中包含大鼠ense2γ神经元基因的启动子，驱动表达编码大鼠甘氨酸受体β亚基的cDNA，后面跟着SV40小T抗原的剪接和polyadenylation信号。456线型的双杂合和纯合转基因小鼠（Glrbspa纯合背景）大脑中，通过Northern和Western blot分别检测到Glrb mRNA和膜结合的甘氨酸受体α1亚基，其水平与非转基因的Glrbspa纯合个体相似。尽管如此，来自纯合转基因小鼠脊髓膜样组织对士的宁的结合显著高于非转基因动物，尽管浓度仍较低。（来源：J:32212, J:60037）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
