插入了一个含有诺卡因抗性基因和一个5' loxP座的FRT引导选择载体,它位于exon 4的上游,然后在exon 5的下游插入了另一个loxP位点。之后,通过与携带Tg(ACTFLPe)9205Dym转基因小鼠杂交,这个选择元件在目标性状的转基因小鼠中被成功去除。(来源:J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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