使用内皮特异性受体酪氨酸激酶的启动子驱动cre重组酶的表达。产生了九条奠基品系,其中一条在有效剔除基因方面表现出色。cre在胚胎期7.5时在中胚层的血管岛中活跃,8.5时在背主动脉中活跃,到11.5时则存在于所有血管的内皮细胞中。(来源:J:102190)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
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