在exon 1的上游插入了一个loxP位点,然后在exon 2下游紧接一个由FRT引导的PGKneo cassette的loxP座。之后,通过与携带Tg(ACTFLPe)9205Dym转基因小鼠杂交,从定向靶向的鼠中去除了选择座。(来源:J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
--
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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