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中文
(tetO)7-FasL基因是这样设计的：在943bp的murine Fas配体(FasL)编码序列前方，有一个Tet响应元件(TRE)，后面跟着牛生长激素的内含子和polyA序列。Tet响应元件(TRE)包含了7个42bp的tet操作子序列(tetO)，位于一个基本的CMV启动子上游。建立了5个奠基品系(A-E)。来自品系D的奠基小鼠显示有20个拷贝的转基因，并且对doxycycline诱导的FasL转录mRNA水平处于中等水平。(J:137382)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
