Tg(Slc32a1-icre/ERT2)3Gloss

The mouse bacterial artificial chromosome (BAC) RP23-392P11 containing the Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, gene, was modified by insertion of sequence encoding iCreER at the Slc32a1 translation initiation ATG, and addition of a Kozak sequence upstream of the ATG. This BAC also contains these additional genes Adig (adipogenin), Arhgap40 (Rho GTPase activating protein 40), AK134637, BC072662, and Actr5 (P5 actin-related protein 5 homolog (yeast)). The modified BAC was used to generate the VGAT-iCreER transgene, which was microinjected into C57BL/6NTac fertilized eggs. Founder line 3 was subsequently established. (J:173675)