The transgene contains the human alpha-synuclein (SNCA) gene driven by a mouse thymus cell antigen 1 (Thy-1) promoter. Line 12 inserted into the gene at 14719103-14719104 (Build GRCm38/mm10) resulting in a duplication. The duplication results in a functional knock-out of Slc4a7 in homozygous mice. (J:173668)