Cre介导的重组通过删除了Trp53tm1.1Awbr的3号和4号外显子,这两个外显子编码了前122个氨基酸,包括转录激活和富含脯氨酸的区域。预测的蛋白质对应于源自4号内含子一个替代转录起始点的人类等位基因delta133p53。(来源:J:173271)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count