在 intron 1 和 intron 2 内分别插入了 loxP 立场和含 FRT 标记的氨苄西林抗性筛选元件,随后通过表达来源于 Gt(ROSA)26 Sor 拓扑异构酶的 flp 复制酶的 mice 来剔除这个筛选元件。这使得 exon2 被 loxP 立场所环绕。(来源:J:173284)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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