将一个包含三个读框中五个终止密码子的neo抗性基因和人PML-RARA融合蛋白的盒式载体插入到5'非翻译区。通过脾细胞的 Western Blot 分析确认了无蛋白表达。(来源:J:172024)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Targeted
插入
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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