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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Pml
tm1(PML/RARA)Ley
Alias:
mPML-PRflox
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基础信息
表型特征
文献报道
将一个包含三个读框中五个终止密码子的neo抗性基因和人PML-RARA融合蛋白的盒式载体插入到5'非翻译区。通过脾细胞的 Western Blot 分析确认了无蛋白表达。(来源:J:172024)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5014059
C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Targeted
插入
--
1
1
4
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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