1和2号外显子的编码区域被新插入的neo cassette替换。通过未刺激和马拉色西亚刺激下的硫代硫酸钠诱导的腹膜巨噬细胞的 Western blot分析,证实了蛋白表达的缺失。(来源:J:172959)
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The coding region of exon 1 and 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on unstimulated and Malassezia-stimulated thioglycolate-elicited peritoneal macrophages. (J:172959)