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在第二外显子上游插入了loxP位点。在第二外显子下游插入了一个带有3' loxP的FRT引导的neo cassette。通过Flp介导的重组移除了neo cassette，然后通过cre介导的重组删除了第二外显子。通过肌肉、肺、肝、脾、肾、尾巴、大脑、心脏、胸腺和骨髓衍生的巨噬细胞提取物的 Western blot 分析，确认了蛋白表达的缺失。(来源：J:173213)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
