人类的PDGFB启动子驱动表达的是一个带有93位氨基酸由异亮氨酸替换成甲硫氨酸的人类UCHL1基因克隆(cDNA)。产生了两条转基因小鼠线,L线相较于H线的转录本表达量较低。在L线中,转录只在雄性小鼠中检测到。(来源:J:128045)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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