使用含PGK-neo cassette的靶向载体,插入了位于exon 41外侧的loxP位点和选择子,随后通过Cre介导的重组,移除了exon 41以及FRT标记的neo cassette。(来源:J:172418, J:188435)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count