从第三到第五外显子(或前三段编码外显子)被靶向。对组织匀浆进行的 Western blot 分析证实了转基因纯合小鼠肠和肝脏组织中没有蛋白质表达。(来源:J:171883, J:236296)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Targeted
基因内删除
--
1
2
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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