这个转基因包含了Cre重组酶编码序列、Wnt1基本启动子和内含子之间的金属硫蛋白1polyadenylation信号,随后是来自Hoxb1基因座的反向四边形4('r4')增强子和'r3/r5'抑制子。这些元件共同限制了在发育胚胎后脑的四边形4区域的表达(来源:J:20433, J:197162)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CD-1
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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