在内皮4号染色体上插入了由loxP位点引导的诺卡因抗性基因座,通过doxorubicin处理的小鼠胚胎干细胞的western blot分析证实了蛋白表达量降低。这个等位基因是部分功能缺失的。(来源:J:171821)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入
--
1
65
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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