将一个cre/ERT2片段插入到包含人介导的invulucrin(IVL)启动子、SV40内含子和SV40polyA信号的载体中。转基因构建通过微注射技术注入到受精卵中,成功产生了三个转基因品系。表达模式通过与ROSA-YFP报告小鼠的杂交进行筛选。(来源:J:172048)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count